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Hairy cell leucemia variant

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Hairy Cell Leukemia Variant, a New Entity of the WHO

Hairy cell leukemia variant (HCLV) is an example of an unclassifiable splenic Bcell leukemialymphoma. It is included in the World Health Organization (WHO) classification as a provisional entity, no longer biologically related to classic HCL.

Hairy Cell Leukemia HCL and Hairy Cell Leukemia Variant

Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. Hairy cell leukemiavariant, or HCLV, is usually described as a prolymphocytic variant of hairy cell leukemia.

HCL-V Hairy Cell Leukemia Foundation

Feb 11, 2015 Hairy cell leukemia variant is a chronic lymphoproliferative disorder whose characteristics resemble the classic form and SMZL, making differential diagnosis essential for therapeutic followup, as hairy cell leukemia variant has a decreased response to drugs prescribed for the classic form.

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